Polycystic ovarian syndrome (PCOS) is the most common endocrine problem in women and one of the leading reasons for female infertility. It is often associated with depression and other mood disorders as well as metabolic dysfunction, including insulin resistance and compensatory hyperinsulinaemia associated with altered androgen production and metabolism. The cause of PCOS is complex and variable and can manifest itself through a spectrum of symptoms, including infertility, amenorrhoea, multiple ovarian cysts, acne, hirsutism and obesity.
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